Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 2'-deoxy-5-ethynyl-uridine
Purity: ≥98%
Formula Markup: C11H12N2O5
Formula Weight: 252.2
CAS Number: 61135-33-9
Notes: 5-Ethynyl-2'-deoxyuridine (EdU) is a nucleoside analog of thymidine that is used to monitor de novo DNA synthesis through click chemistry.{32475,32476} Like 5-bromo-2’-deoxyuridine (BrdU; Item No. 15580), EdU is incorporated into DNA during active DNA synthesis. It can then be detected using a fluorescent azide probe and copper catalysis using 1,3-dipolar cycloaddition.{32476} Modified nucleosides, including EdU, can be cytotoxic when added to cells for prolonged periods.{32477}