Agerafenib, CAS 1188910-76-0

Product Description: Agerafenib (CEP-32496; RXDX-105) is a highly potent and orally efficacious inhibitor of BRAFV600E with a Kd of 14 nM.

Applications: Cancer-Kinase/protease

Formula: C24H22F3N5O5

References: [1]Rowbottom MW, et al. Identification of 1-(3-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea hydrochloride (CEP-32496), a highly potent and orally efficacious inhibitor of V-RAF murine sarcoma viral oncogene homologue B1 (BRAF) V600E.

CAS Number: 1188910-76-0

Molecular Weight: 517.46

Compound Purity: 99.63

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Raf

• SKU: MEXHY-15200-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-15200-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK