Alflutinib (mesylate), CAS 2130958-55-1

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N-[2-[[2-(dimethylamino)ethyl]methylamino]-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-2-propenamide, monomethanesulfonate

Purity: ≥98%

Formula Markup: C28H31F3N8O2 / CH3SO3H

Formula Weight: 664.700329

CAS Number: 2130958-55-1

Notes: Aflutinib is an inhibitor of mutant EGFRs.{54445} It is selective for EGFRL858R, EGFRG719X, EGFRL858R, EGFRL861A, and EGFRT790M mutant EGFRs over wild-type EGFR. Aflutinib (10 and 30 mg/kg) reduces tumor growth in an EGFRL858R and EGFRT790M-expressing LU1868 non-small cell lung cancer (NSCLC) patient-derived xenograft (PDX) mouse model.

• SKU: CAY31473-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 31473-25
• Package Unit: 25 mg
• Quantity Unit: STK