AP26113, CAS 1197953-54-0

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 5-chloro-N4-[2-(dimethylphosphinyl)phenyl]-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-2,4-pyrimidinediamine

Purity: ≥98%

Formula Markup: C29H39ClN7O2P

Formula Weight: 584.1

CAS Number: 1197953-54-0

Notes: AP26113 is an orally bioavailable inhibitor of anaplastic lymphoma kinase (ALK; IC50 12087), ceritinib (Item No. 19374), and CH5424802 (Item No. 18516).{31962,31296} AP26113 blocks ALK activity and reduces growth in neuroblastoma cells, mouse xenograft, and Drosophila model systems harboring constitutively active ALK variants.{31963}

• SKU: CAY19778-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 19778-25
• Package Unit: 25 mg
• Quantity Unit: STK