Product Description: Apraclonidine hydrochloride (ALO 2145), a selective α2 and weak α1 receptor agonist activity, effectively lowers intraocular pressure (IOP) in human eyes. Apraclonidine hydrochloride is a topical ophthalmic solution and has the ability to elevate the eye lid[1][2].
Applications: Neuroscience-Neuromodulation
Formula: C9H11Cl3N4
References: [1]Wijemanne S, et al. Apraclonidine in the treatment of ptosis. J Neurol Sci. 2017;376:129‐132./[2]Searles RV, et al. Aqueous humor dynamics in anesthetized rats infused with intracameral apraclonidine. Pharmacology. 1999;58(4):220‐226./[3]Yoriko Hayasaka, et al. Effects of topical antiglaucoma eye drops on prostaglandin E(2)-induced aqueous flare elevation in pigmented rabbits. Invest Ophthalmol Vis Sci
CAS Number: 73218-79-8
Molecular Weight: 281.57
Compound Purity: 98.96
Research Area: Neurological Disease
Solubility: DMSO : 125 mg/mL (ultrasonic)/H2O : ≥ 12.5 mg/mL
Target: Adrenergic Receptor
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