Product Description: AS057278 is a potent, selective, orally active and blood-brain barrier (BBB) penetrant non-peptidic D-amino acid oxidase (DAAO) inhibitor with an IC50 value of 0.91 μM and EC50 of 2.2-3.95 μM. AS057278 can normalize phencyclidine (PCP)-induced prepulse inhibition in mice. AS057278 can be used for researching schizophrenia[1].
Applications: Neuroscience-Neuromodulation
Formula: C5H6N2O2
References: [1]Adage T, et al. In vitro and in vivo pharmacological profile of AS057278, a selective d-amino acid oxidase inhibitor with potential anti-psychotic properties. Eur Neuropsychopharmacol. 2008;18(3):200-214.
CAS Number: 402-61-9
Molecular Weight: 126.11
Compound Purity: 99.76
Research Area: Neurological Disease
Solubility: DMSO : ≥ 100 mg/mL
Target: Others