Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 6-[[(4R,5S,6S)-2-carboxy-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-yl]thio]-6,7-dihydro-5H-pyrazolo[1,2-a][1,2,4]triazol-4-ium, inner salt
Purity: ≥95%
Formula Markup: C15H18N4O4S
Formula Weight: 350.39398
CAS Number: 120410-24-4
Notes: Biapenem is a broad-spectrum β-lactam antibiotic.{47703,47704} It is active against aerobic and anaerobic, Gram-positive and Gram-negative bacteria, including clinical isolates of E. coli, oxacillin-sensitive S. aureus, B. fragilis, and Clostridium (MIC90s = 0.12, 0.12, 0.25, and 1 μg/ml, respectively). It is also active against the rifampicin-susceptible H37Rv and rifampicin-resistant 115R and 124R M. tuberculosis strains (MICs = 2-4, 4-8, and 8-16 mg/L, respectively).{47705} Biapenem (200 mg/kg) decreases the number of lung colony-forming units (CFUs) in a mouse model of late-phase acute H37Rv M. tuberculosis infection.
English
Deutsch
