BYK204165, CAS 1104546-89-5

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 4-[(1-methyl-1H-pyrrol-2-yl)methylene]-1,3(2H,4H)-isoquinolinedione

Purity: ≥98%

Formula Markup: C15H12N2O2

Formula Weight: 252.3

CAS Number: 1104546-89-5

Notes: BYK204165 is a selective inhibitor of poly(ADP-ribose) polymerase 1 (PARP1; IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay).{22587} It is selective for PARP1 over PARP2 (IC50 = 4,168 nM for murine PARP2 in an enzyme assay). BYK204165 inhibits hydrogen peroxide-activated PARP in A549 human lung epithelial, C4I human cervical, and H9c2 rat cardiac myoblast cells with IC50 values of 229.09, 1,778.28, and 123.03 nM, respectively.

• SKU: CAY21430-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 21430-1
• Package Unit: 1 mg
• Quantity Unit: STK