Product Description: Go6976 is a Protein Kinase C (PKC) inhibitor, with an IC50 of 20 nM.
Applications: COVID-19-immunoregulation
Formula: C24H18N4O
References: [1]Qatsha KA, et al. Gö 6976, a selective inhibitor of protein kinase C, is a potent antagonist of human immunodeficiency virus 1 induction from latent/low-level-producing reservoir cells in vitro. Proc Natl Acad Sci U S A. 1993 May 15;90(10):4674-8./[2]Hayamitsu Adachi, et al. Microbial metabolites and derivatives targeted at inflammation and bone diseases therapy: chemistry, biological activity and pharmacology. The Journal of Antibiotics volume 71, pages 60–71 (2018)./[3]Mahmoudian S, et al. Influenza A virus proteins PB1 and NS1 are subject to functionally important phosphorylation by protein kinase C. J Gen Virol. 2009;90(Pt 6):1392-1397.
CAS Number: 136194-77-9
Molecular Weight: 378.43
Compound Purity: 99.57
Research Area: Cancer
Solubility: DMSO : 50 mg/mL (ultrasonic)
Target: Influenza Virus;PKC
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