GSK-626616, CAS 1025821-33-3

Product Description: GSK-626616 is a potent, orally bioavailable inhibitor of DYRK3 (IC50=0.7 nM). GSK-626616 inhibits other members of the DYRK family (e.g., DYRK1A and DYRK2) with similar potency, which is a potential therapy for the treatment of anemia[1].

Applications: COVID-19-immunoregulation

Formula: C18H10Cl2N4OS

References: [1]Connie L. Erickson-Miller, et al. GSK626616: A DYRK3 Inhibitor as a Potential New Therapy for the Treatment of Anemia. Blood 2007 110:510;/[2]Wippich F, et al. Dual specificity kinase DYRK3 couples stress granule condensation/dissolution to mTORC1 signaling. Cell. 2013;152(4):791-805.

CAS Number: 1025821-33-3

Molecular Weight: 401.27

Compound Purity: 99.77

Research Area: Cardiovascular Disease

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: DYRK

• SKU: MEXHY-105309-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-105309-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK