IKK-16 (hydrochloride), CAS 1186195-62-9

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: [4-[(4-benzo[b]thien-2-yl-2-pyrimidinyl)amino]phenyl][4-(1-pyrrolidinyl)-1-piperidinyl]-methanone, monohydrochloride

Purity: ≥98%

Formula Markup: C28H29N5OS / HCl

Formula Weight: 520.1

CAS Number: 1186195-62-9

Notes: IKK-16 is a potent inhibitor of IκB kinases (IKKs), displaying IC50 values of 200, 40, and 70 nM for IKKα, IKKβ, and IKK complex, respectively, in cell-free assays.{29522} It is effective in cells and in animals and has been used delineate the role of NF-κB signaling in diverse contexts.{29517,29521,29518,29519} IKK-16 has also been reported to inhibit protein kinase D isoforms and the ATP-binding cassette (ABC) transporter ABCB1.{29520,29516}

• SKU: CAY13313-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 13313-25
• Package Unit: 25 mg
• Quantity Unit: STK