The ability to modulate the life or death of a cell has a huge therapeutic potential. When apoptosis works overly well, too many cells may die and the result may be grave tissue damage. This is the case in neurodegenerative disorders such as Alzheimer, Huntington and Parkinson diseases. On the other hand, when apoptosis does not work, cells become immortal as occurs in cancer. Therefore, analysis of the cell cycle machinery and signaling pathways that control the cell cycle is widely studied.
Read here our new article about apoptosis. Still one of the most important research areas!