Pellitorine, CAS 18836-52-7

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: (2E,4E)-N-(2-methylpropyl)-2,4-decadienamide

Purity: ≥95%

Formula Markup: C14H25NO

Formula Weight: 223.4

CAS Number: 18836-52-7

Notes: Pellitorine is an amide alkaloid that has been found in P. nigrum and has diverse biological activities.{49685,49686,49687,49688} Pellitorine is cytotoxic to HL-60 leukemia and MCF-7 breast cancer cells (IC50s = 13 and 1.8 µg/ml, respectively).{49687} It inhibits production of TNF-α, IL-1α, and IL-1β and phosphorylation of ERK1/2 induced by high mobility group protein B1 (HMGB1) in human umbilical vein endothelial cells (HUVECs) when used at concentrations of 10 and 20 µM.{49688} Pellitorine (9 µg/animal, i.v.) prolongs survival time in a mouse model of sepsis induced by HMGB1.

• SKU: CAY11662-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 11662-25
• Package Unit: 25 mg
• Quantity Unit: STK