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ADC Related

ADC Related

The ADC, antibody-drug conjugate, a humanised or human monoclonal antibody with conjugated highly potent cytotoxic small molecules (payloads), is a novel therapeutic format with great potential for a paradigm shift in cancer chemotherapy. The three components of the ADC form a powerful oncolytic agent capable of delivering normally untolerated cytotoxins directly to cancer cells, which then internalise and release the cytotoxic drugs. Currently, two ADCs, Adcetris and Kadcyla, have received marketing authorisation and more than 40 others are in clinical development.

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  1. MC-Gly-Gly-Phe-Gly-GABA-Exatecan, CAS 1599439-52-7
    MC-Gly-Gly-Phe-Gly-GABA-Exatecan, CAS 1599439-52-7
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    Sku MEXHY-160649-5
    Manufact. SkuHY-160649-5
    Packaging Unit5 mg
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  2. MC-Gly-Gly-Phe-Gly-GABA-Exatecan, CAS 1599439-52-7
    MC-Gly-Gly-Phe-Gly-GABA-Exatecan, CAS 1599439-52-7
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    Sku MEXHY-160649-10
    Manufact. SkuHY-160649-10
    Packaging Unit10 mg
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  3. Exatecan-amide-bicyclo(1.1.1)pentan-1-ol, CAS 2866299-06-9
    Exatecan-amide-bicyclo(1.1.1)pentan-1-ol, CAS 2866299-06-9
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    Sku MEXHY-160597-0
    Manufact. SkuHY-160597-0
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  4. Exatecan-amide-CH2-O-CH2-CH2-OH, CAS 2920907-39-5
    Exatecan-amide-CH2-O-CH2-CH2-OH, CAS 2920907-39-5
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    Sku MEXHY-160543-0
    Manufact. SkuHY-160543-0
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  5. TAM557, CAS 1802499-20-2
    TAM557, CAS 1802499-20-2
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    Sku MEXHY-160473-0
    Manufact. SkuHY-160473-0
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  6. MC-Gly-Gly-Phe-Gly-NH-CH2-O-cyclopropane-CH2COOH, CAS 2922606-39-9
    MC-Gly-Gly-Phe-Gly-NH-CH2-O-cyclopropane-CH2COOH, CAS 2922606-39-9
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    Sku MEXHY-160453-0
    Manufact. SkuHY-160453-0
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  7. MC-Val-Cit-PAB-Ispinesib, CAS 1629737-40-1
    MC-Val-Cit-PAB-Ispinesib, CAS 1629737-40-1
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    Sku MEXHY-160441-5
    Manufact. SkuHY-160441-5
    Packaging Unit5 mg
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  8. MC-Val-Cit-PAB-Ispinesib, CAS 1629737-40-1
    MC-Val-Cit-PAB-Ispinesib, CAS 1629737-40-1
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    Sku MEXHY-160441-10
    Manufact. SkuHY-160441-10
    Packaging Unit10 mg
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  9. PBX-7011 (mesylate)
    PBX-7011 (mesylate)
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    Sku MEXHY-160438A-0
    Manufact. SkuHY-160438A-0
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  10. Mal-GGG-Bal-NHS ester, CAS 1193111-65-7
    Mal-GGG-Bal-NHS ester, CAS 1193111-65-7
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    Sku MEXHY-160408-5
    Manufact. SkuHY-160408-5
    Packaging Unit5 mg
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