Clone Name: HL10
Light Chain: Kappa
Product Description: KRAS has the distinction of being a preeminent oncoprotein as it is mutated in more than 85% of RAS-altered cancers. The RAS (G12D Mutant) antibody [HL10] is the first commercially available recombinant antibody that demonstrates exceptional specificity by paraffin-embedded immunohistochemistry and western blot for the RAS G12D mutant protein.
Application Note: WB: 1:500-1:3000. IHC-P: 1:25-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Positive Control: 293T transfected NRAS(G12D) , AsPC1 , HPAC , HPAF-II , PANC1 , SU86.86
Form: Liquid
Buffer (with preservative): PBS, no Preservative.
Concentration: 1.5 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species: Human
Immunogen: Carrier-protein conjugated synthetic peptide surrounding mutant G12D of human K-Ras. The exact sequence is proprietary.
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
English
Deutsch
