Product Description: Tetrahydropiperine, a cyclohexyl analogue of piperine, is the first natural aryl pentanamide from Piper longum[1]. Tetrahydropiperine (compound 14) inhibits the cytochrome P450 (CYP) isoform CYP1A1/arylhydrocarbon hydroxylase (AHH; IC50=23 µM)[2].
Applications: Cancer-programmed cell death
Formula: C17H23NO3
References: [1]Madhusudhan P, et al. Tetrahydropiperine, the first natural aryl pentanamide from Piper longum. Biochem Syst Ecol. 2001 May;29(5):537-538./[2]Koul S, et al. Structure-activity relationship of piperine and its synthetic analogues for their inhibitory potentials of rat hepatic microsomal constitutive and inducible cytochromeP450 activities. Bioorg Med Chem. 2000 Jan;8(1):251-68.
CAS Number: 23434-88-0
Molecular Weight: 289.37
Compound Purity: 99.41
Research Area: Cancer
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Cytochrome P450
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