BDE 47, CAS 5436-43-1

Product Description: BDE 47 targets mitochondria, inhibits mitochondrial oxidative phosphorylation (OXPHOS), decreases mitochondrial membrane potential (MMP) and induces apoptosis in embryonic cell. BDE 47 induces the generation of ROS, and activates the JNK signaling pathway. BDE 47 exhibits embryonic developmental toxicity in zebrafish[1].

Applications: Cancer-Kinase/protease

Formula: C12H6Br4O

References: [1]Zhuang J, et al., BDE-47 induced apoptosis in zebrafish embryos through mitochondrial ROS-mediated JNK signaling. Chemosphere. 2020 Nov;258:127385.

CAS Number: 5436-43-1

Molecular Weight: 485.79

Compound Purity: 98.37

Research Area: Cancer; Neurological Disease

Target: Apoptosis;JNK;Oxidative Phosphorylation;Reactive Oxygen Species

• SKU: MEXHY-W762011-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W762011-10.1
• Package Unit: 10mM/1mL
• Quantity Unit: STK