N-desmethyl Loperamide, CAS 66164-07-6

Shelf life (days): 1825.0

Formulation: A crystalline solid

Formal Name: 4-(4-chlorophenyl)-4-hydroxy-N-methyl-α,α-diphenyl-1-piperidinebutanamide

Purity: ≥98%

Formula Markup: C28H31ClN2O2

Formula Weight: 463.0

CAS Number: 66164-07-6

Notes: Loperamide (Item No. 14875) is an opiate which potently and selectively activates μ opioid receptors (Ki = 0.16 nM) exclusively in the periphery.{23761,23758} N-desmethyl Loperamide is a major metabolite of loperamide.{26350,26349} Like loperamide, N-desmethyl loperamide is a substrate of the ATP-dependent efflux transporter, P-glycoprotein.{26349,26352} As a result, both the parent compound and the metabolite display restricted passage through the blood-brain barrier.{26352,26348} N-desmethyl Loperamide in biological samples can be analyzed by a variety of methods.{26350,26353}

• SKU: CAY16126-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 16126-1
• Package Unit: 1 mg
• Quantity Unit: STK
• Application: Reinstoffe, Isotopenmarkierung