SW033291, CAS 459147-39-8

Shelf life (days): 730.0

Formulation: A crystalline solid

Formal Name: 2-(butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridine-3-amine

Purity: ≥95%

Formula Markup: C21H20N2OS3

Formula Weight: 412.6

CAS Number: 459147-39-8

Notes: The enzyme 15-hydroxy prostaglandin dehydrogenase (15-PGDH) initiates the catabolism of PGs and related eicosanoids.{20452,20456}. SW033291 is a potent inhibitor of 15-PGDH (Ki = ~0.1 nM) that has activity in vivo.{29053} It rapidly increases the levels of PGE2 in bone marrow and other tissues in mice after intraperitoneal injection.{29053} SW033291 accelerates hematopoietic recovery in mice receiving bone marrow transplant and promotes tissue regeneration in mouse models of colon and liver injury.{29053}

• SKU: CAY18040-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 18040-5
• Package Unit: 5 mg
• Quantity Unit: STK