WYE-132, CAS 1144068-46-1

Product Description: WYE-132 (WYE-125132) is a highly potent, ATP-competitive, and specific mTOR kinase inhibitor (IC50: 0.19±0.07 nM; >5,000-fold selective versus PI3Ks). WYE-132 (WYE-125132) inhibits mTORC1 and mTORC2.

Applications: Cancer-Kinase/protease

Formula: C27H33N7O4

References: [1]Yu K, et al. Beyond rapalog therapy: preclinical pharmacology and antitumor activity of WYE-125132, an ATP-competitive and specific inhibitor of mTORC1 and mTORC2.Cancer Res. 2010 Jan 15;70(2):621-631.

CAS Number: 1144068-46-1

Molecular Weight: 519.60

Compound Purity: 99.90

Research Area: Cancer

Solubility: DMSO : 25 mg/mL (ultrasonic)

Target: Apoptosis;mTOR

• SKU: MEXHY-10044-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-10044-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK