XAP044, CAS 196928-50-4

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 7-hydroxy-3-(4-iodophenoxy)-4H-1-benzopyran-4-one

Purity: ≥98%

Formula Markup: C15H9IO4

Formula Weight: 380.1

CAS Number: 196928-50-4

Notes: XAP044 is an antagonist of the metabotropic glutamate (mGlu) receptor 7 (mGluR7), inhibiting lateral amygdala long term potentiation in brain slices from wild-type mice with an IC50 value of 88 nM.{30926} This effect is absent in mGluR7-deficient mice. XAP044 demonstrates good brain penetrance, producing wide spectrum anti-stress and antidepressant- and anxiolytic-like efficacy in rodent behavioral tests.{30926}

• SKU: CAY19095-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 19095-5
• Package Unit: 5 mg
• Quantity Unit: STK